Probiotics And Long Covid
Health Notes 051126
Here is one of our latest natural health and nutrition findings:
Do multi-strain probiotics improve long covid symptoms?
University of Belgrade (Serbia), March 27 2026 (News-Medical)
A new study in Microorganisms suggests that multi-strain probiotics can produce modest, targeted shifts in the gut microbiome of people with long COVID.
Probiotics are increasingly being explored as a potential way to support recovery in people with long COVID.
The investigators conducted a double-blinded, prospective, non-randomized interventional study with self-reported compliance monitoring. One arm included 23 participants with long COVID, and 26 fully convalescent patients. Long COVID patients had a history of symptoms for 3-27 months after the primary infection, with a median of 14 months.
The probiotic formulation contained Saccharomyces boulardii, Lacticaseibacillus rhamnosus GG, and two Lactiplantibacillus plantarumstrains. The gut microbiome was assessed by fecal analysis using 16S rRNA gene amplicon sequencing (V3–V4 region).
Functional prediction analysis suggested that probiotics in long COVID could increase bacterial energy metabolism and reduce oxidative stress, as inferred from pathway enrichment, reflecting predicted changes consistent with improved microbial respiration.
Several of the enriched genera are associated with anti-inflammatory processes, which could aid recovery from long COVID-19.
Biochemical tests showed consistent, though modest, trends toward normalcy with supplementation. Overall, probiotic intervention demonstrated microbiota-status-dependent potential in long COVID recovery.The probiotic formulation was supported in part by an industry source, though the funder reportedly had no role in study design, analysis, or interpretation.
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